This happens when there’s long-term damage to the kidneys due to intrinsic kidney disease. When there isn’t enough blood flowing to the kidneys for an extended period of time, the kidneys begin to shrink and lose the ability to function. Causes also include toxin overload and ischemia, which is a lack of oxygen to the kidneys. Acute intrinsic kidney failureĪcute intrinsic kidney failure can result from direct trauma to the kidneys, such as physical impact or an accident. This type of kidney failure can usually be cured once your doctor determines the cause of the decreased blood flow. The kidneys can’t filter toxins from the blood without enough blood flow.

Insufficient blood flow to the kidneys can cause acute prerenal kidney failure. There are five different types of kidney failure: Acute prerenal kidney failure chemotherapy drugs that treat cancer and some autoimmune diseases.thrombotic thrombocytopenic purpura, a disorder that causes blood clots in small vessels.scleroderma, an autoimmune condition that affects your skin.multiple myeloma, a cancer of the plasma cells in your bone marrow.hemolytic uremic syndrome, which involves the breakdown of red blood cells following a bacterial infection, usually of the intestines.glomerulonephritis, an inflammation of the small blood vessels of the kidneys.

lupus, an autoimmune disease that can cause inflammation of many body organs.

vasculitis, an inflammation of blood vessels.

an overload of toxins from heavy metals.

Some other things that may lead to kidney failure include:

damage to your nerves that control your bladder.

Other conditions can interfere with urination and possibly lead to kidney failure, including: Some cancers can block the urine passageways, such as: When your body can’t eliminate urine, toxins build up and overload the kidneys. High blood pressure and anti-inflammatory medications can also limit blood flow.

Some conditions that cause loss of blood flow to the kidneys include: People who are most at risk usually have one or more of the following causes: Loss of blood flow to the kidneysĪ sudden loss of blood flow to your kidneys can prompt kidney failure. The cause typically also determines the type of kidney failure. Kidney failure can be the result of several conditions or causes.

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